The SINTER Study examines bone strength, influenced by genetics, aging, and lifestyle. Osteoporosis, linked to low bone mass and high fracture risk, worsens with age
Gene: Basic unit of inheritance passed from parent to child
Craft: Skill and experience
GeneCraft.nl comprises the expertise and experience of the Genomics Medicine team at the Department of Internal Medicine in Erasmus MC. Our group is committed to transforming genomic discoveries into tangible clinical solutions for individuals vulnerable to common complex disorders with emphasis on the musculoskeletal system.
Lines of research
Translational Genomics
Translational Genomics, where cutting-edge genetic research meets practical healthcare solutions. Our focus includes personalized treatments, genomics-assisted decision-making, and integrating clinical and population-based studies. We aim to improve patient outcomes, enhance disease understanding, and develop targeted interventions.
Deep (musculo) skeletal phenotyping
Our research enhances musculoskeletal health by analyzing bone density, body composition, muscle strength, and spinal alignment. We improve fracture risk prediction and develop interventions through advanced analytical tools, including machine learning, applied to Big Data from population and patient cohorts, integrating genetics, environment, and lifestyle for better health outcomes.
Projects
Featured Staff
Xinpeng He
PhD Researcher
My PhD topic is Exploring the effects of exposome factors on musculoskeletal traits. Osteoporosis is considered as a systemic multifactorial disease caused by a combination of genetic, environmental, and lifestyle factors. “Exposome” was first defined by Wild as the totality of human environmental (meaning all non-genetic) exposures from conception onwards, complementing the genome.
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My favorite food is Cantonese cuisine. And l love playing basketbal
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